Premanand A.

A highly skilled biotechnologist and computational biologist with expertise in various bioinformatic analysis works, including Microarray and NGS data analysis, SNP analysis, biological network construction and analysis, protein ligand docking, molecular dynamic simulation studies, and more. Looking to apply my knowledge and experience to help others in the field achieve their goals. Contact me for Gene Expression analysis: Differential Gene expression analysis of microarray and NGS data in R using Bioconductor NGS data Analysis - SNP analysis Computer Aided Drug Designing (CADD) Structure Based Virtual Drug Screening Homology Modelling Ligand Library generation and drug screening Molecular Docking Molecular Dynamic Simulation Studies using GOMACS - (CHARMM & GROMOS forcefield). 16S Sequencing analysis 1. Data split and reads merging 2. Data quality control: data filtration and chimera removal 3. OTUs (Operational Taxonomic Units) Clustering and Species annotation，including OTUs Heatmap, GraPhlAn display, Taxonomy Tree, KRONA results 4. Species distribution, including Ternary plot , Species Abundance Heatmap, the evolutionary tree in genus 5. Alpha-diversity Analysis, including Alpha Indices table (Observed species, Good's coverage, Chao1, ACE, Shannon, Simpson, PD whole tree), Species diversity curves, Species accumulation boxplot, 6. Venn and Flower diagram 7. Beta-diversity Analysis, including Beta diversity heatmap, (un)weighted unifrac distance analysis, PCA (Principal Component Analysis), PCoA (Principal Co-ordinates Analysis), UPGMA (Unweighted Pair-group Method with Arithmetic Means), Anosim, MRPP, Adonis, Amova analysis, Species T-test analysis, MetaStat, LEfSe analysis.